Aging takes place rapidly when hormone levels start to decrease. The body undergoes changes with the decrease of hormone levels in the body. Weight gain is faster, depression is more frequent, which indicate the drop of natural hormone. HGH deficiency is a kind of disorder of hypothalamus, pituitary gland or the secretion of the growth hormone in children. HGH deficiency can occur anytime during infancy or childhood. Children are dependent on HGH for normal growth. Problems related to HGH deficiency are different at different stages of life. Excessive growth hormone in children can also lead to gigantism or tall stature whereas in adults it an cause swelling of soft tissues, high BP, excessive hair growth, too much sweating, large hands, feet and face.

HGH deficiency can be substituted with identical HGH through injections into the blood stream. HGH injections were used in late 1950's for children having growth disorders. HGH injections were first meant for children with stunted growth. Growth hormones are secreted by the pituitary gland and affects child's growth. A child who is deficient with growth hormone grows less than 2 inches in a year. In most children with deficient growth hormone the growth slows down after the age of two or three. Stunted growth in children due to corticosteroid treatment along with low bone density in children can also be avoided with HGH. Treating low bone mineral density in children can take a longer time.

Human growth hormone is given to children with short stature, kidney failure, with Prader-Willie syndrome and with Turner's syndrome. HGH is also administered in children with growth failure with proven levels of low or absolutely no growth hormone , children with poor bone growth, AIDS, Short Bowel syndrome in which children do not eat food as there is very little bowel left, wounds to heal after burns that are of third degree types that take a longer time to heal.

Early diagnosis is very important for a child deficient with growth hormone. A child must be diagnosed and treated at a very young age. Accurate annual measurements and child's growth chart should be maintained so that the growth hormone deficiency can be treated before the bones fuse.

Every child does not react to the growth hormone treatment alike. Most of the children under growth hormone therapy reach the normal adult height. Growth hormone therapy is given by injection daily or several times in a week. The body undergoes changes with the decrease of hormone levels in the body.